Journal La Medihealtico

Knowledge and Application of Pharmacist Ethical Practices in Surakarta City

Rara Denise Pasesa — 2024-03-26

This study aims to determine the knowledge and application of pharmacist ethical practices in the city of Surakarta. This research is a type of descriptive research. This research was conducted in all pharmacies and hospitals in the Surakarta City area. Data collection will take place in November 2023-January 2024. The population in this study was 489 and the error rate was 5%, so the sample taken was 205 people. The selection of respondents in this study was carried out by non-probability sampling techniques with a sampling technique, namely purposive sampling. The instrument used in this study was a questionnaire. Data analysis of this study was carried out by descriptive analysis on SPSS software. Based on the results of the study, pharmacists were dominated by good knowledge as many as 132 respondents (64%) while for the application of pharmacist ethical practices in Surakarta City was dominated by the application of ethics as many as 122 respondents (60%). This study concludes that pharmacists in Surakarta City have good knowledge of ethical practices and sufficient application of ethical practices.

Knowledge and Application of Pharmacist Ethics Practices in Pekalongan Regency

Diva Adistya — 2024-04-02

This study aims to determine the knowledge and application of pharmacist ethical practices in Pekalongan Regency. This study is a type of observational descriptive study, the population in this study is pharmacists who practice in Pekalongan Regency as many as 129 using purposive sampling, the sample in this study was obtained as many as 100 respondents. The instrument used in this study was a questionnaire. This research will be conducted in Pekalongan district from October to December 2023. Data analysis of this study was carried out by descriptive analysis on SPSS software. The results showed that out of 100 respondents, 97 respondents (97%) had good knowledge about pharmacist ethical practices. However, out of 100 respondents, 52 respondents (52%) dominated the application of pharmacy ethical practices in the less category. It can be concluded that although pharmacists have good knowledge in pharmacist ethical practices, in the application of pharmacist ethical practices compared to the best, which is less.

Factors Related to Glaucoma Patients at the Main Outpatient Clinic of Medan Eye Center

Okkis Razuansyah Siregar — 2024-04-02

Glaucoma is a condition where eye pressure damage the optic nerve. Usually, high eye pressure will gradually damage the optic nerve fibers, resulting in disruption of the field of vision. Galucoma is the second most common cause of blindness in the world after cataracts. This study aims to determine the factors associated with glaucoma sufferers. The research conducted is analytic in nature with a case control study design that aims to see the relationship of the independent variables. Data obtained from medical records that met the inclusion criteria were 55 medical record data. Because it met the inclusion criteria, all data was used as a researchsample (total sampling). The result of this study show that of the 4 risk factors for glaucoma patients, all have a relantionship of the occurrence of glaucoma. Calculated Chi-Square value with < p=0,05), this shows that there is a significant relationship between risk factors for glaucoma sufferers. It is hoped that every health service center will routinely provide education to patients about the importance of regular eye health checks. In order to be able to detect more quickly if you have early symptoms of eye disorders.

Toothpaste Formulation Combination of Andaliman Fruit and Kecombrang Flowers as a Cleaner and Antibacterial

Muhammad Gunawan — 2024-05-01

Currently on the market there are many circulating toothpastes for cleaning teeth and treatment, but they contain synthetic chemicals that can cause health problems, such as fluoride and sodium lauryl sulfate (SLS). This material can irritate the gums and mouth, gums feel burning, sensitive teeth and discomfort on the tongue. Traditionally, andaliman fruit has been used as a refreshing and deodorizing agent and prevents tooth decay by gargling for about 10 minutes. One natural ingredient that has been proven to have antibacterial activity and has often been used to eliminate bad breath and body odor is combrang flower (Etlinger elatior Jack). Therefore, the author utilizes the combination of andaliman fruit and combrang flowers in toothpaste formulations with the aim of obtaining a natural toothpaste that is relatively safe and economical. The formulation of toothpaste preparations uses a combination of andaliman fruit and combrang flowers concentrations of 2.5%, 5%, and 10% with a ratio (75:25); (50:50); and (25:75). Evaluation of the preparation includes tests of homogeneity, pH, stability, cleaning power, organoleptic with hedonic test, irritation test of volunteer skin, and antibacterial activity against mutant Streptococcus and Escherichia coli. Toothpaste preparations containing a combination of dry pollen of combrang flowers and andaliman fruit have good cleaning power, no irritation, and can eradicate Streptococcus mutans and Escherichia coli bacteria with strong categories. The best formula is with the content of combrang flowers and andaliman fruit 75:25, because although the cleaning power is smaller, it has the strongest antibacterial, so the resulting toothpaste provides benefits for cleaning and dental care, safe and economical.

The Effect of Giving Celery Extract on Testicular Function of Wistar White Rats Exposed to Lead Acetate

Evi Mefriyanti — 2024-05-03

The population is unaware of lead poisoning risks. Lead can cause tissue function and metabolism issues. Celery (Apium graveolens L), an antioxidant, is widely used in medicine and as a multivitamin. This study examines how celery extract affects SOD levels and testicular Caspase-3 expression in lead-exposed Wistar white rats (Rattus norvegicus). The accurate experiment-based quantitative research. 27 Wistar white rats (Rattus norvegicus) were sampled. This study examined celery extract as an independent variable and SOD and caspase-3 expression as dependent variables. Three treatment groups were presented: Control Group, Treatment Group 1 with 200 mg/kg BW celery extract, and Treatment Group 2 with 400 mg/kg BW. The Paired T-test and normality test were performed. SPSS 26.0 processed statistical data. The study indicated that celery extract increased SOD levels, but not as much as without lead introduction. Also, the caspase-3 decrease was not significant. In normality tests, SOD and caspase-3 were p > 0.05. Similarly, the Paired T-test showed 0.000 < 0.05 for SOD caspase-3 levels. Celery leaf extract (Apium graveolens Linn) at 200 and 400 mg/kg BW provided active components like alkaloids, flavonoids, saponins, tannins, and steroids, which were beneficial. The body benefits from its antioxidant properties.

Different Effects of Hylocecarus Polyrhizus and Hylocecarus Undatus Extract on Reducing Total Cholesterol of Male Rattus Norvegicus Wistar Strain

Elviza Fahriani — 2024-05-03

A chronic ailment that is caused by excessive food consumption and a lack of physical activity, obesity is a condition that may be prevented. The tropical dragon fruit can control cholesterol levels, support the immune system, and give a natural colorant for culinary applications. In a true experimental research, sample with rats were fed red and white dragon fruit extracts to determine the amounts of cholesterol in their bodies. Spectrophotometry was used to determine the rats' blood lipid profiles, cholesterol levels, and body weight after they were fed a meal that was high in fat and contained duck egg yolk. For this study, extracts from red and white dragon fruits were administered to male Wistar rats to determine their effects on cholesterol levels. After fourteen days, both groups had a reduction in high cholesterol levels, with group 4 exhibiting the most significant drop in cholesterol levels. Additionally, the extracts decreased the levels of MDA while simultaneously increasing the levels of SOD. The most significant rise was seen in group 4, given white dragon fruit extract at 140 mg/200 gr BW daily. SPSS was utilized to analyze the effects of dragon fruit on blood cholesterol levels in experimental animals, employing the LSD technique and one-way ANOVA.

A Systematic Review of Knowledge and Perception Regarding Generic Medicines Among Indonesians

Siti Pandanwangi TW — 2024-05-03

Generic medicines are a type of medicine with an official name that has been assigned to the efficacious substance it contains. Generic medicines have the same effectiveness as patented medicines. Many people think that generic medicines are of low quality, so they prefer branded generic medicines or patented medicines. This systematic review aims to report the results of a search for previously reviewed studies that focus on the level of public knowledge and perception of generic medicines. The research method used is a literature study method using journal data from the last 10 years. Journal collection was carried out by searching online journal databases indexed in Google Scholar, and PubMed using Mesh (Medical Subject Headings) with a focus on the keywords "knowledge", "perception", and "generic medicines". The results of this research are that the level of Indonesian people's knowledge of generic medicines is quite good but not evenly distributed, especially among groups of people who have a strong belief that cheap medicines are of lower quality. Acceptance of generic medicines tends to be higher in communities with higher levels of education. Communities with low socio-economic conditions generally have a low level of education so they tend to have greater distrust of generic medicines. This research concludes that it is important to provide information about generic medicines aggressively and continuously to the public to increase public trust in generic medicines. In addition, prescribing generic medicines by physicians is the main thing to eliminate public distrust about generic medicines.

Potential Role of Propolis Flavonoid on Malondialdehyde and Superoxide Dismutase Levels on Endometriosis

Citra Krisna Mayasari — 2024-05-03

Endometriosis is a prevalent gynecological condition that affects around 10% of women within the reproductive age group globally. Recent research indicates that oxidative stress plays a significant role in the development of endometriosis. The present administration of progestin hormone treatment has been shown to induce additional oxidative stress, which is characterized by elevated levels of oxidative stress indicators, including malondialdehyde (MDA), and a reduction in the enzymatic antioxidant superoxide dismutase (SOD). The presence of hormonal imbalances in conjunction with these alterations fosters an environment conducive to the metastasis of endometrial cells. This process initiates inflammatory pathways, angiogenesis, and the formation of lesions and tumors, ultimately exacerbating the state of endometriosis. Research findings indicate that propolis has inherent antioxidant properties, characterized by a high concentration of flavonoid components and phenolic acids. Propolis contains active compounds that have the ability to trap free radicals by forming more stable molecules. Propolis has anti-inflammatory, antimicrobial, and immunomodulatory characteristics, hence potentially enhancing the patient's oxidative stress state, mitigating morbidity, and reducing the duration of hospitalization. This research aims to assess the possible impact of flavonoids found in propolis on the treatment of endometriosis.

Relationship between Nutritional Status and Postoperative Outcomes of Breast Cancer

Andi Ismawardany Imran — 2024-05-03

Breast cancer is the most common cancer in the world which is expected to increase morbidity and mortality rates . Nutritional status is an indicators that can be used to predict post-operative breast cancer outcomes . Breast cancer patients with poor / more nutritional status has a higher risk of experiencing more post-operative complications . This study was conducted to determine the nutritional status with post-operative outcomes in breasts Cancer patients. To determine the relationships between nutritional status (BMI) and post-operative outcomes in breast cancer patients at the Ibnu Sina Hospital Makassar. This study is cross -sectional analytic study, using a total sampling method with a total of 55 samples from patients medical records . Data analysis used the Chi- square test to assess whether there was a relationship. Obtained a significant relationships between nutritional status and length of stay (p = 0.002), and lymphedema (p = 0.027). While the relationships between nutritional status and post-operative wound complications was obtained (p = 0.052), .” history (p = 0.171). There is a relationships between nutritional status and post-operative outcomes for breasts Cancer.